Engineering a Biomimetic Quantum Dot-Functionalized Hydrogel Scaffold for Accelerated Wound Repair: A Regenerative Medicine Approach
Articles in Press, Accepted Manuscript Available Online from 22 October 2025
Articles in Press, Accepted Manuscript Available Online from 22 October 2025
An increasing amount of attention is being paid to the process of developing and designing effective wound dressings in order to increase wound healing qualities. To facilitate the healing process, we developed a novel wound dressing. A biomimetic hydrogel scaffold containing ZnO quantum dots (ZnO-QDs) is utilized in the formation of the dressing. In order to investigate the structure of the hydrogel, we first synthesized it and then used SEM, TEM, and XRD investigations. We put the scaffold through its paces on rats that contained excisional wounds and compared the results to those of a control group. Additionally, we carried out histological examinations on each of the groups and assessed the rate of healing. When compared to the control group, the wound dressing that contained ZnO quantum dots sped up the process of wound contraction and improved the healing process. It was determined by histological examination that advanced re-epithelialization and collagen deposition had occurred. The utilization of this scaffold presents a novel approach to the management of regenerative wounds.
